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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MPP5 All Species: 26.97
Human Site: T238 Identified Species: 42.38
UniProt: Q8N3R9 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N3R9 NP_071919.2 675 77294 T238 E M Q L E P I T D E R V Y E S
Chimpanzee Pan troglodytes XP_510014 764 85553 T327 E M Q L E P I T D E R V Y E S
Rhesus Macaque Macaca mulatta XP_001105724 674 77301 T237 E M Q L E P I T D E R V Y E S
Dog Lupus familis XP_547862 675 77214 T238 E M Q L E P F T D E R V Y E S
Cat Felis silvestris
Mouse Mus musculus Q9JLB2 675 77211 T238 E M Q L E P I T D E R V Y E S
Rat Rattus norvegicus Q5U2Y3 576 65604 Q203 K R P E E I I Q I L S Q S Q G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505475 675 76860 T238 E M Q P E S L T D E R V Y E S
Chicken Gallus gallus Q5ZJ00 468 52501 V98 N D K Q S C M V A R I F H G G
Frog Xenopus laevis NP_001085267 675 76810 S238 E M M P E P S S E D C F Y E N
Zebra Danio Brachydanio rerio Q8JHF4 677 76390 P240 M Q L E P L V P S V N A S E T
Tiger Blowfish Takifugu rubipres P49697 467 52590 S97 L N D K Q R C S V A R I L H G
Fruit Fly Dros. melanogaster Q24210 898 100893 L474 P P P M V P Y L N G D E L D N
Honey Bee Apis mellifera XP_393395 1033 115664 P577 S S S S P S G P P S P T S S W
Nematode Worm Caenorhab. elegans P54936 961 108794 P418 Y D K I K A L P C E P V V T E
Sea Urchin Strong. purpuratus XP_784409 971 107892 T533 P D P A E L P T D V Y Q D I D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.6 97 98.2 N.A. 96.7 36.2 N.A. 93.7 25 86 77 25.7 26.7 34.7 24.1 34.7
Protein Similarity: 100 87.5 97.7 99.5 N.A. 98.6 54.9 N.A. 96.8 43.8 92.5 86.7 44.5 46.3 49.2 41.7 49.2
P-Site Identity: 100 100 100 93.3 N.A. 100 13.3 N.A. 80 0 40 6.6 6.6 6.6 0 13.3 20
P-Site Similarity: 100 100 100 93.3 N.A. 100 26.6 N.A. 86.6 20 66.6 20 26.6 33.3 0 40 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 0 7 0 0 7 7 0 7 0 0 0 % A
% Cys: 0 0 0 0 0 7 7 0 7 0 7 0 0 0 0 % C
% Asp: 0 20 7 0 0 0 0 0 47 7 7 0 7 7 7 % D
% Glu: 47 0 0 14 60 0 0 0 7 47 0 7 0 54 7 % E
% Phe: 0 0 0 0 0 0 7 0 0 0 0 14 0 0 0 % F
% Gly: 0 0 0 0 0 0 7 0 0 7 0 0 0 7 20 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 7 7 0 % H
% Ile: 0 0 0 7 0 7 34 0 7 0 7 7 0 7 0 % I
% Lys: 7 0 14 7 7 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 7 0 7 34 0 14 14 7 0 7 0 0 14 0 0 % L
% Met: 7 47 7 7 0 0 7 0 0 0 0 0 0 0 0 % M
% Asn: 7 7 0 0 0 0 0 0 7 0 7 0 0 0 14 % N
% Pro: 14 7 20 14 14 47 7 20 7 0 14 0 0 0 0 % P
% Gln: 0 7 40 7 7 0 0 7 0 0 0 14 0 7 0 % Q
% Arg: 0 7 0 0 0 7 0 0 0 7 47 0 0 0 0 % R
% Ser: 7 7 7 7 7 14 7 14 7 7 7 0 20 7 40 % S
% Thr: 0 0 0 0 0 0 0 47 0 0 0 7 0 7 7 % T
% Val: 0 0 0 0 7 0 7 7 7 14 0 47 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % W
% Tyr: 7 0 0 0 0 0 7 0 0 0 7 0 47 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _